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H. Mohamed, K. E., & Mirghani, S. (2017). Breast Cancer Case Using Tamoxifen during Pregnancy: A Case Report and Literature Review. Sudan Journal of Medical Sciences (SJMS), 12(2), 114-118. https://doi.org/10.18502/sjms.v12i2.921

https://doi.org/10.18502/sjms.v12i2.921

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  • Kamal Eldein H. Mohamed
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  • Sarah Mirghani
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Published Date

  • Jul 4, 2017

Breast Cancer Case Using Tamoxifen during Pregnancy: A Case Report and Literature Review

Sudan Journal of Medical Sciences (SJMS) / Sudan JMS: Volume 12 (2017), Issue No. 2 / Pages 114-118

Abstract

This is a case of 32 years old nulliparous female who was diagnosed  in November 2004 as a case of carcinoma of the right breast , luminal A , (Estrogen Receptor positive Progesterone receptor negative, Her 2 negative, Ki67 10 %), poorly differentiated invasive ductal cancer, TNM stage,T2 N0 MO.  She had a wide local excision and axillary clearance. As she is a case of low risk early stage luminal A breast cancer; she was not given chemotherapy, instead she had a course of external irradiation and was put on Tamoxifen (Astra Zeneca, 20 mg daily), and was advised not to get pregnant during this treatment,but she got pregnant and delivered normally a healthy infant, although Tamoxifen is potentially teratogenic.

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