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Ngassaki-Yoka, C.-D., Ndong, J. M. N., & Bisseye, C. (2018). ABO, Rhesus blood groups and transfusion-transmitted infections among blood donors in Gabon. Sudan Journal of Medical Sciences (SJMS), 13(1), 12-21. https://doi.org/10.18502/sjms.v13i1.1685

https://doi.org/10.18502/sjms.v13i1.1685

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  • Cited by 5 articles

authors

  • Christ-Dominique Ngassaki-Yoka
    No author data available.
  • Jophrette Mireille Ntsame Ndong
    No author data available.
  • Cyrille Bisseye
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Published Date

  • Mar 14, 2018

ABO, Rhesus blood groups and transfusion-transmitted infections among blood donors in Gabon

Sudan Journal of Medical Sciences (SJMS) / Sudan JMS: Volume 13 (2018), Issue No. 1 / Pages 12-21

Abstract

Background: Few studies focused on the study of blood groups in Gabon. This study aimed to determine the phenotypic frequency of ABO and Rhesus antigens in blood donors of Libreville and to assess the association between ABO blood groups and transfusion-transmitted infections.

Materials and Methods: The study of ABO and Rhesus blood groups concerned 4,744 blood donors. ABO and Rhesus phenotyping were obtained using monoclonal monospecific antisera: anti-A, anti-B, anti-AB, anti-D, anti-E, anti-C, anti-c, and anti-e with an automate (QWALYS® 3, DIAGAST, France) or a card gel (ID Card, BIO-RAD) according to manufacturer’s instructions.

Results: The phenotypic frequency of blood group antigens A, B, AB and O were respectively 21.0%; 17.6%; 2.6% and 58.9%. Those of rhesus antigens D, d, C, c, E and e were 97.7%; 2.3%; 15.9%; 99.9%; 17.6%; 99.3%, respectively. The prevalence of ABO and Rh antigens in Gabonese donors reported here are significantly different from those of neighboring countries. No association was found between the prevalence of HIV, HCV and syphilis and ABO blood groups. Instead, HBV seroprevalence was twice as high among non-O blood groups donors compared with blood group O donors [OR = 2 (CI 1.26 to 3.2), p = 0.003].

Conclusions: This study provides new data on phenotypic frequency of ABO and Rh blood groups in a representative sample of the Gabonese blood donor population. It suggests a significant association between ABO blood group and HBV infection.

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